Question: |
What are the benefits and limitations of PSA (Prostate Specific Antigen) screening for prostate cancer? |
Category: |
Diseases & Conditions > Cancer |
Keywords: |
benefits, limitations, PSA, test, screen, prostate cancer |
Type: |
what |
Rating: (0 ratings) Views: 260 Discussions: 0 In Watch Lists: 1 |
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Answer:
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Benefits of Screening
- Early detection and treatment of potentially curable stage of prostate cancer (i.e., better chances of survival with localized disease). Reassurance of being at low risk for prostate cancer.
- Prostate Specific Antigen (PSA) can be obtained with a simple blood test and is widely available.
Limitations of Screening
- Survival benefit from prostate cancer screening has not been demonstrated in rigorous trials.
- False positive result may lead to increased anxiety and having to experience the discomfort and possible complications associated with biopsy (e.g., pain, hematospermia/hematuria, and infection).
- Prostate cancer may be slow growing and may never advance or progress to cause significant disease or death. Treatment can cause both short- and long-term side effects (e.g., pain, urinary incontinence, and impotence).
- False reassurance from a normal test (false negative), leading to a delayed diagnosis of prostate cancer.
Source: Agency for Healthcare Research and Quality, U.S. Department of Health & Human Services
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What are the benefits and limitations of PSA (Prostate Specific Antigen) screening for prostate cancer?
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